Friends, dolo 650 and Calpol 650, two are very common names that commonly used by Indian people. At least everybody knows the name of this drug even though they have not consumed it. These both are over the counter drugs means you can get them directly from the local pharmacy near to you. This is used for any type of pain are fever. Friends, I know the pain when your loved one suffered from fever at midnight and you have nobody to suggest which drug to be given to reduce fever. Even though you know the name of the drug, but afraid to give it without any consultation.
Today in this article I will give some idea regarding the use of dolo 650, dolo 500 or calpol650, calpol500 drugs so that there will be no confusion whenever you need it.
What is paracetamol
The content of dolo 650 or Calpol 650 is the same. The active ingredient is known as Paracetamol. In India, we are used to the name Paracetamol but in some countries, they use the word acetaminophen. These both are nothing but the same name. The chemical formula of Paracetamol is [N-]acetyl-para-aminophenol. . Hence these two names that mean Paracetamol or acetaminophen both derived from the chemical name.
How to take dolo 650
Just like any drug we know that you are very cautious about its use. But with dolo 650 or dolo 500, you can use it without much fear. Generally, you have to take this drug with a meal. The advantage of taking drugs with meals is that you will not get your stomach to irritate. That means, with some drugs, our stomachs start burning due to increase acidity levels. If we take such drugs with a meal, then we can prevent our burning pain. And the Second benefit is faster absorption of drugs. With the absorption of food drugs also gets observed.
Frequency of intake calpol 500/ calpol 650
You can take this tablet 6 hourly in 24 hours. That means you can take it 4 times a day. But even taking drugs 3 times a day is sufficient for any mild fever or pain. Everybody has a question how to take 4 times?
You can adjust your time to 7 am 1 pm, 7 pm, 12 pm, assuming that your bedtime is 12 at the night.
But when somebody has a fever or pain, he may go to sleep early or can wake up late in the morning. Hence he can be disturbed by such 4 times doses. In this situation, you should follow 3 times doses in 24 hours. These doses can be as effective as 4 times doses. The schedule could be 9 am 3 pm & 9 pm. This can be followed easily.
If there is a fever at the night after sleep, then you can give a tablet immediately.
One thing I want to tell you if you have a fever a night or in a day time, when you cannot take breakfast or any type of meal, then also you can take this tablet without fear without any type of meal intake.
For single dose there will be no problem to your stomach but for multiple dose you have to keep in mind in that it has to be taken with meal.
Actually Dolo 500 and calpol 500 are used for fever. And Dolo 650 and calpol 650 are used for any type of 10 for body ache. But if at home only 650 is available and you have fever then don’t worry you can take it for fever also. For single dose there will be no any problem.
The safety index of this drug is very high. That means at large dose also it will not cause any toxicity for any individual.
In case of small baby, adolscent and infant, this drug proved to be very safe. but in infant, children and adults and you must have knowledge of dose.
For calculation of dose 15mg per kilogram per dose can be given to any baby.
Means for 10 kg baby 15×10 kg = 150 mg.
It is always written on all tab and syrup about the concentration.
In calpol 250 , each 5 ml contain 250 mg. means each ml contain 50 mg.
If we need only 150 mg, then take 3ml as dose.
My opinion to take half ml more than required, because this much amount always remains sticked to plastic measuring cup.
Formulation of Paracetamol
Paracetamol is very safe in case of infants, childs, adolescents, pregnancy, adults.
Hence it is available in all types of formulations.
For infant it is available as drops.
For child it is available as syrup.
For adolescent it is available as half dose tablets i.e kid tablets.
for adult it is available as tablet 500 and 650 strength
For admitted patient in hospital , it is available at intravenous infusion also .
It is available pessary formulation.
It is a small rod-like tablet, which can be insert inside rectum through anal canal. Commonly this type of drug used for children undergoing surgery. It avoid oral intake and gastric irritation and also avoid iV infusion.
All these formulations are very effective as Antipyretic, means in case of fever and Analgesic, to reduce pain.
Indication of Paracetamol
It is indicated for any type of fever and in any type of pain.
The drug which reduces fever is known as antipyretic and the drug which reduces pain is known as analgesic.
Paracetamol act both way. It is is antipyretic as well as analgesic. It comes under the group NSAID. The long form of this is non steroid anti inflammatory drug. Means this drug is not steroid, but still it can act lover inflammation, like steroid drug.
Many of you may be using this drug for fever only but you can use it for any type of pain.
As analgesic
Body ache,
Mild muscle ache,
Mind to toothache,
Any type of pain due to trauma.
Any type of headache,
Any type of localised swelling and pain,
As antipyretic
Fever due to malaria,
Fever due to pharyngitis,
Fever due to tonsillitis,
Fever due to gastroenteritis,
Your due to vaccination,
Fever due to cough and cold,
Fever due to any type of unknown Pathology,
Means for any type of fever, you can take this drug.
Basically for fever, use 500 Drug dose, 4 times a day, and for pain, use 650 Drug dose for day.
Mechanism of action
After taking as a Tablet paracetamol gets absorbed from small intestine. If you swallow the tablet in empty stomach then effects of Paracetamol will start after 30 minute. And if you take it with any type of food material then it will start after 45 minutes to 1 hour. In both cases the maximum level of Paracetamol achieved after 1 hour.
It is a cox 1 and Cox 2 receptor inhibitor drug ,which block cyclooxygenase pathway,which is a mechanism of action for this drug.
What are the side effects
Generally paracetamol is well tolerated by all patients and very few side effects are seen for short time therapy. If anybody taking it on long term,then side effects such as stomach pain, stomach ulceration, kidney failure symptoms can be seen.
But for a very short duration like 5 to 10 days, side effects are never seen and one should not be worried while taking this tablet. You can say this is a very safe drug and no side effect. Except in some individuals, immediate fullness of abdomen, burning sensation in the stomach, are seen.
Drug interaction with paracetamol
There is no interaction seen with commonly used drug but some drugs may have some reaction.
Interaction is the word used when to drug combine in our body and produces any different unlikely result.
If you are already taking any analgesic then effect of analgesic may be increased and that may be harmful for the kidney. That is known as accentuation effects.
Many analgesics have paracetamol as a combination drug also. So before taking paracetamol you must stop any analgesic if you are taking it.
Dolo 650, Calpol 650, both drugs are very safe in case of pregnant women too.
Special things to note
If You have a small baby, child, adolescent in your home then you must have calpol syrup or calpol Tablet in your home.
You may be aware of the dose requirement because these are the most frequently prescribed drugs by all the doctors. hence you may have an idea of what your paediatrician prescribed for your baby in the last visit. you can use that dose without any hesitation, whenever your baby have fever in midnight.
you need not to be worried that you have not consulted any doctor before giving this drug.
And if you have no idea about dosing then keep in mind the average dose requirement for all these groups.
Either you calculate the dose as 15 mg per kg per dose or give as below.
In the case of Infant means if your baby is less than one year then you must use Calpol drop.
The drop means the syrup which has a dropper inside it. The dropper is calibrated as 1 ml only.
so you can use half an ml to 1 ml dose for up to 1 year.
Means if your baby is 6 months to 1 year then you can give 1 ml dose.
If your baby is 1 year to 2.5 years, then you can use calpol syrup 125, as 5 ml dose.
If your baby is more than 2.5 years to 5 years, then calpol 250 as 5ml dose.
If your baby is more than 6 years to 14 year then you can use calpol 250 as 7.5 ml dose.
In case you have an adolescent, then you can use paracetamol tablet 500 mg on an emergency basis to reduce fever. you can safely use 500 mg tablet after 14 years of age.
this is a rough idea of the dosing of Paracetamol.
FAQs
What if the baby vomits after taking Calpol syrup?
If the baby vomits in less than 30 minutes after having a dose of Calpol syrup, then give the same dose again.
If he or she vomits more than 30 minutes after, do not give another dose, until the next normal dose.
When will baby fever reduce?
Usually you it start reducing after half-hour. Its full effect comes after 1 hour. Sometimes fever will not reduce completely. But don’t worry. Do not repeat the dose immediately. You can repeat the dose as early as after 4 hours.
How often can I take Calpol 650mg Tablet?
You should only take four doses of Calpol 650mg Tablet in 24 hours. But Routinely 3 doses are sufficient. If still, you are having pain, you need to consult a doctor.
Is Calpol act as an antibiotic too?
No, it is not an antibiotic.
If still, you have some queries regarding this drug, please share your question with us at pmpitambar@gmail.com
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